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Organische Chemie – Arbeitsgruppe Professor Dr. Frank Hahn

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Frank Hahn Frank Hahn
Frank Hahn

Faculty of Biology, Chemistry & Earth Science
Organic Chemistry (Food Chemistry)


Curriculum vitae

10.1999 – 02.2005Chemistry studies in Karlsruhe, Bonn and Paris
05.2003 – 07.2003Research stay in the laboratory of Dr. E. Rose
Université Pierre et Marie Curie-Paris VI
09.2004 – 02.2005Diploma thesis in Bioorganic Chemistry with
PD Dr. U. Schepers and Prof. Dr. K. Sandhoff
Kekulé-Institute, University of Bonn
Synthesis of polyamine conjugates
04.2005 – 07.2008PhD thesis in Bioorganic Chemistry with
PD Dr. U. Schepers and Prof. Dr. S. Bräse
Kekulé-Institute, University of Bonn
Polyamine solid phase synthesis and biological evaluation of the target compounds
08.2008 – 02.2009Postdoctoral research associate in the field of Bioorganic Chemistry
Kekulé-Institute, University of Bonn
03.2009 – 07.2011Postdoctoral Research Associate with Prof. Dr. Peter F. Leadlay
Department of Biochemistry, University of Cambridge (UK)
Investigation of polyketide biosynthetic pathways
05.2011 – 10.2015Junior Research Group Leader
Institute of Organic Chemistry, Leibniz University of Hannover
From 01.2013Emmy Noether Research Group Leader
Centre for Biomolecular Drug Research
From 11.2015W2 Professor for Organic Chemistry
Department of Chemistry, Faculty BCG, University of Bayreuth


Awards and Fellowships

02.2018Young Investigator Award for Natural Products Research of the DECHEMA
since 01.2013Emmy Noether Research Group of the DFG
08.2011 – 07.2015Career Integration Grant of the EU
08.2009 – 07.2011Intra European Fellowship of the EU
03.2009 – 07.2009Research stipend of the DFG
10.2005Diploma Grant from the Theodor-Layman Foundation


Selected Presentations

  • Sino-German Frontiers of Science (SinoGFoS) Symposium 2018 – Shanghai (PRC) – 19.04.2018
  • British-German Frontiers of Science (BriGFoS) Symposium 2018 – Dorking (UK) – 21.03.2018
  • DPhG-Seminar – Institute of Pharmaceutical Sciences – University of Freiburg – 08.11.2017
  • Directing Biosynthesis V (Offered Lecture) – Warwick (UK) – 22.03.2017
  • Symposium “Small Molecules & Microbes” – University of Konstanz – 10.10.2016
  • Institute seminar – Clemens-Schöpf-Institut für Organische Chemie und Biochemie – TU Darmstadt – 12.04.2016
  • 51. Naturstofftreffen – Universität Bayreuth – 08.04.2016
  • 28. Irseer Naturstofftage (Opening Lecture “Nachwuchswissenschaftler stellen sich vor“) – Kloster Irsee – 24.02.2016
  • Natural Products: Beilstein Organic Chemistry Symposium 2015 (Invited Lecture) – Prien (Chiemsee), Germany – 29.09.2015
  • 23. Nachwuchswissenschaftlersymposium Bioorganik – Hamburg – 23.09.2015
  • Colloquium in Organic Chemistry and Chemical Biology – Fachbereich Chemie – Philipps Universität Marburg – 09.07.2015
  • Institutssseminar – Institute of Organic Chemistry and Biochemistry – TU Munich – 16.06.2015
  • Directing Biosynthesis IV (Offered Lecture) – Norwich (UK) – 25.03.2015
  • 22. Nachwuchswissenschaftlersymposium Bioorganik – Tübingen – 26.09.2014
  • 21. Nachwuchswissenschaftlersymposium Bioorganik – Rostock – 03.09.2012

Selected Publications

Research articles

K. H. Sung, G. Berkhan, T. Hollmann, L. Wagner, W. Blankenfeldt, F. Hahn
Insights into the dual Activity of a Bifunctional Dehydratase-Cyclase Domain
Angew. Chem. Int. Ed. 2018, 57, 343-347; Angew. Chem. 2018, 130, 349-353.

G. Berkhan, C. Merten, C. Holec, F. Hahn
The Interplay between a Multifunctional Dehydratase Domain and a C-Methyltransferase Effects Olefin Shift in Ambruticin Biosynthesis
Angew. Chem. Int. Ed. 2016, 55, 13589-13592; Angew. Chem. 2016, 128, 13787–13790.

G. Berkhan, F. Hahn
A Dehydratase Domain in Ambruticin Biosynthesis Displays Additional Activity as a Pyran-Forming Cyclase
Angew. Chem. 2014, 126, 14464-14468; Angew. Chem. Int. Ed. 2014, 53, 14240-14244.

N. Kandziora, J. N. Andexer, S. J. Moss, B. Wilkinson, P. F. Leadlay, F. Hahn
Uncovering the Origin of Z-Configured Double Bonds in Polyketides: Intermediate E-Double Bond Formation During Borrelidin Biosynthesis
Chem. Sci. 2014, 5, 3563-3567.

Review articles

F. Hemmerling, F. Hahn
Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides
Beilstein J. Org. Chem. 2016, 12, 1512-1550.

S. Friedrich, F. Hahn
Opportunities for Enzyme Catalysis in Natural Product Chemistry
Tetrahedron 2015, 71, 1473–1508.

A. Kirschning, F. Hahn
Merging Chemical Synthesis and Biosynthesis: A New Chapter in the Total Synthesis of Natural Products and Natural Product Libraries
Angew. Chem. 2012, 124, 4086-4096; Angew. Chem. Int. Ed. 2012, 51, 4012-4022.

Frank Hahn

Faculty of Biology, Chemistry & Earth Science
Organic Chemistry (Food Chemistry)


Frank Hahn
Group leader

Adress: Universität Bayreuth, 95440 Bayreuth
Room: U 05 (B12)
Consultation time: Wednesday 3.00-3.30 p.m. in room U 05 (B12).

Telefon: +49 (0)921 / 55-3660
E-Mail: frank.hahn@uni-bayreuth.de

Verantwortlich für die Redaktion: Tim Hollmann

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