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Organic Chemistry Prof. Dr. Frank Hahn

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Overview
Overview
Frank Hahn Frank Hahn
Frank Hahn

Faculty of Biology, Chemistry & Earth Science
Organic Chemistry (Food Chemistry)


Curriculum vitae

since 11.2015W2 Professor for Organic Chemistry (Food Chemistry)
Department of Chemistry, Faculty BCG, University of Bayreuth
01.2013 – 12.2018Emmy Noether Research Group Leader
Institute of Organic Chemistry & Centre for Biomolecular Drug Research, Leibniz University of Hannover and University of Bayreuth
05.2011 – 10.2015Junior Research Group Leader
Institute of Organic Chemistry, Leibniz University of Hannover
03.2009 – 07.2011Postdoctoral Research Associate with Prof. Dr. Peter F. Leadlay
Department of Biochemistry, University of Cambridge (UK)
Investigation of polyketide biosynthetic pathways
08.2008 – 02.2009Postdoctoral research associate in the field of Bioorganic Chemistry
Kekulé-Institute, University of Bonn
04.2005 – 07.2008PhD thesis in Bioorganic Chemistry with
PD Dr. U. Schepers and Prof. Dr. S. Bräse
Kekulé-Institute, University of Bonn
Polyamine solid phase synthesis and biological evaluation of the target compounds
09.2004 – 02.2005Diploma thesis in Bioorganic Chemistry with
PD Dr. U. Schepers and Prof. Dr. K. Sandhoff
Kekulé-Institute, University of Bonn
Synthesis of polyamine conjugates
05.2003 – 07.2003Research stay in the laboratory of Dr. E. Rose
Université Pierre et Marie Curie-Paris VI
10.1999 – 02.2005Chemistry studies in Karlsruhe, Bonn and Paris


Awards and Fellowships

10.2021 – 09.2028Momentum initiative of the VolkswagenStiftung
07.2019 – 06.2020Exploration Grant of the Boehringer Ingelheim Foundation
02.2018Young Investigator Award for Natural Products Research of the DECHEMA
01.2013 – 06.2019Emmy Noether Research Group of the DFG
08.2011 – 07.2015Career Integration Grant of the EU
08.2009 – 07.2011Intra European Fellowship of the EU
03.2009 – 07.2009Research stipend of the DFG
10.2005Diploma Grant from the Theodor-Layman Foundation


Selected Presentations

  • MegaSyn Symposium on Megasynthases – Bad Nauheim – 01.10.2020
  • Sino-German Frontiers of Science (SinoGFoS) Symposium 2018 – Shanghai (PRC) – 19.04.2018
  • British-German Frontiers of Science (BriGFoS) Symposium 2018 – Dorking (UK) – 21.03.2018
  • DPhG-Seminar – Institute of Pharmaceutical Sciences – University of Freiburg – 08.11.2017
  • Directing Biosynthesis V (Offered Lecture) – Warwick (UK) – 22.03.2017
  • Symposium “Small Molecules & Microbes” – University of Konstanz – 10.10.2016
  • Institute seminar – Clemens-Schöpf-Institut für Organische Chemie und Biochemie – TU Darmstadt – 12.04.2016
  • 51. Naturstofftreffen – Universität Bayreuth – 08.04.2016
  • 28. Irseer Naturstofftage (Opening Lecture “Nachwuchswissenschaftler stellen sich vor“) – Kloster Irsee – 24.02.2016
  • Natural Products: Beilstein Organic Chemistry Symposium 2015 (Invited Lecture) – Prien (Chiemsee), Germany – 29.09.2015
  • 23. Nachwuchswissenschaftlersymposium Bioorganik – Hamburg – 23.09.2015
  • Colloquium in Organic Chemistry and Chemical Biology – Fachbereich Chemie – Philipps Universität Marburg – 09.07.2015
  • Institutssseminar – Institute of Organic Chemistry and Biochemistry – TU Munich – 16.06.2015
  • Directing Biosynthesis IV (Offered Lecture) – Norwich (UK) – 25.03.2015
  • 22. Nachwuchswissenschaftlersymposium Bioorganik – Tübingen – 26.09.2014
  • 21. Nachwuchswissenschaftlersymposium Bioorganik – Rostock – 03.09.2012

Selected Publications

Research articles

J. Wunderlich, T. Roß, M. Schröder, F. Hahn
Step-Economic Synthesis of Biomimetic β-Ketopolyene Thioesters and Demonstration of Their Usefulness in Enzymatic Biosynthesis Studies
Org. Lett. 2020, 22, 4955-4959.

T. Hollmann, G. Berkhan, L. Wagner, K. H. Sung, S. Kolb, H. Geise, F. Hahn
Biocatalysts from Biosynthetic Pathways : Enabling Stereoselective, Enzymatic Cycloether Formation on A Gram Scale
ACS Catal. 2020, 10, 4973-4982.

K. H. Sung, G. Berkhan, T. Hollmann, L. Wagner, W. Blankenfeldt, F. Hahn
Insights into the dual Activity of a Bifunctional Dehydratase-Cyclase Domain
Angew. Chem. Int. Ed. 2018, 57, 343-347; Angew. Chem. 2018, 130, 349-353.

G. Berkhan, C. Merten, C. Holec, F. Hahn
The Interplay between a Multifunctional Dehydratase Domain and a C-Methyltransferase Effects Olefin Shift in Ambruticin Biosynthesis
Angew. Chem. Int. Ed. 2016, 55, 13589-13592; Angew. Chem. 2016, 128, 13787–13790.

G. Berkhan, F. Hahn
A Dehydratase Domain in Ambruticin Biosynthesis Displays Additional Activity as a Pyran-Forming Cyclase
Angew. Chem. 2014, 126, 14464-14468; Angew. Chem. Int. Ed. 2014, 53, 14240-14244.

Review articles

F. Hemmerling, F. Hahn
Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides
Beilstein J. Org. Chem. 2016, 12, 1512-1550.

S. Friedrich, F. Hahn
Opportunities for Enzyme Catalysis in Natural Product Chemistry
Tetrahedron 2015, 71, 1473–1508.

A. Kirschning, F. Hahn
Merging Chemical Synthesis and Biosynthesis: A New Chapter in the Total Synthesis of Natural Products and Natural Product Libraries
Angew. Chem. 2012, 124, 4086-4096; Angew. Chem. Int. Ed. 2012, 51, 4012-4022.

Frank Hahn

Faculty of Biology, Chemistry & Earth Science
Organic Chemistry (Food Chemistry)


Frank Hahn
Group leader

Adress: Universität Bayreuth, 95440 Bayreuth
Room: U 05 (B12)
Consultation time: Wednesday 3.00-3.30 p.m. in room U 05 (B12).

Phone: +49 (0)921 / 55-3660
E-mail: frank.hahn@uni-bayreuth.de

Webmaster: Tim Hollmann

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