Natural product synthesis - Biosynthesis - Biocatalysis
Our group has a general interest in natural products. On the one hand, we pursue the total synthesis of natural products with the aim to develop efficient routes to pharmacologically relevant compounds.
We also carry out detailed studies on the biosynthetic pathways of natural products, that is, the mechanisms by which they are formed in their producing organisms. Based on this knowledge, we develop novel biocatalytic tools, which are used in the chemoenzymatic synthesis of natural products. This combination of chemical and biotechnological elements enables the highly efficient production of natural product derivatives for drug development.
In addition, we strive to further develop the biocatalysts we have discovered into generally applicable tools. An important goal is finding novel accesses to fine chemicals for which no biotechnological manufacturing process currently exists.