Druckansicht der Internetadresse:

Faculty of Biology, Chemistry & Earth Sciences

Organic Chemistry Prof. Dr. Frank Hahn

Print page



Publication in Organic Letters


Our most recent publication in Organic Letters just went online.

Johannes figured out a new way to rapidly assemble biomimetic β-ketopolyene thioesters. These compounds are valuable surrogates for biosynthetic studies, but unfortunately also highly sensitive and problematic in their handling. Key was the use of a one-pot reductive Horner-Wadsworth-Emmons olefination for mild and step-economic backbone elongation and functionalisation. We additionally used the compounds produced for a biochemical study on the stereoselectivity of ketoreductase domains from giant multimodular polyketide synthases.

Find the paper at:


Congratulations to Johannes, Theresa and Marius!

Facebook Twitter Youtube-Kanal Instagram UBT-A Contact